Special remarks: This antiserum is 14-3-3 sigma specific.
In the following we are giving the sequences of the available polyclonal antibodies directed against human 14-3-3 sigma:
Cat.-no.            Site                  sequence
18642               C-Terminal        (C)EEGGEAPQEPQS
18640               Middle              (C)SNEEGSEEKGPEV
18646               N-Terminal        ERASLIQKA(C)

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. This plethora of interacting proteins allows 14-3-3 to play important roles in a wide range of vital regulatory processes, such as mitogenic signal transduction, apoptotic cell death, and cell cycle control.