CCL8/MCP-2 ELISA
Technology | ELISA |
Kit size | 96 |
Sample material | serum, EDTA/Heparin-plasma |
Sample preparation | dilution if necessary |
Sample volume | 100 µl |
Standard range | 3.9 - 250 pg/ml |
Incubation | 1 h (37°C), 30 min (4°C), 30 min at RT |
Measuring system | TMB at 450 nm |
Sensitivity | 1.1 pg/ml |
Special remarks: Chemokine (C-C motif) ligand8/Monocyte chemoattractant protein-2 (CCL8/MCP-2) is constitutionally-classified as C-C subfamily. CCL8/MCP-2 is produced by monocytes, fibroblasts and epithelial cells, and it shows chemotactic activity to CD4+ T cells, CD8+ T cells, monosytes and NK cells. Recently it has been reported that elevated serum levels of CCL8/MCP-2 were found in humans with GVHD (Graft-Versus-Host-Disease) who had undergone HSCT (Hematopoietic stem-cell transplantation) and the report has suggested that CCL8/MCP-2 is a potential biomarker for human GVHD .
