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Demeditec:: Chlamydia pneumoniae IgM ELISA

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Infectious Disease
Cat.-No.: DE3913

Product: Chlamydia pneumoniae IgM ELISA

TEST SPECIFICATIONS

Chlamydia pneumoniae IgM ELISA

Technology

ELISA

Kit size

96 Tests

Sample material

Serum

Sample preparation

1:101 predilution

Sample volume

10 µl

Standard range

Cut-Off

Incubation

60 min at 37°C, 30 & 15 min at RT

Measuring system

TMB at 450 nm

Sensitivity

83.3 %



Special remarks:

Chlamydiae are no motile, Gram negative and obligatory intracellular growing bacteria which form characteristic inclusions within the cytoplasm of parasitized cells. They are easily visible in the light microscope. Three different Chlamydia species pathogenic for humans are known: Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia psittaci, and one species only pathogenic for animals (C. pecorum). Chlamydia trachomatis is the most prevalent agent of sexually transmitted diseases worldwide (400-500 million cases) and the number of infections is constantly growing. Pregnant women infected with C. trachomatis may transmit these bacteria during childbirth, causing conjunctivitis or pneumonia in newborns. Untreated cases of chlamydial infection can lead to chronic salpingitis, possibly resulting in ectopic pregnancy or infertility. In males, C. trachomatis is a major cause of non-gonococcal urethritis. A severe problem in Chlamydia infections is the frequent asymptomatic insidious course which may result in the initiation of chronic diseases. In many instances primary infections are not recognized and only the sequelae caused by ascended, persisting agents are diagnosed.

 

Species

 

Mechanism of infection

 

Disease

 

Diagnostics

 

C. trachomatis

 

 

Direct or sexual transmission:

The primary site of infection usually is the mucous membrane of the eye or the urogenital tract

 

Lymphogranuloma venereum (LGV)

Trachoma

Inclusion conjunctivitis of neonates and adults; Cervicitis, salpingitis, urethritis, epididymitis, proctitis and pneumonia of newborns

 

 

 

Serology

 

PCR

 

Microscopy

 

C. pneumoniae

 

 

Infiltration of the mucous membrane of the

respiratory tract

 

Respiratory diseases

discussed: endocarditis, coronary

heart diseases

 

C. psittaci

 

 

Inhalation of feces from infected birds;

contact with infected avian viscera

 

Ornithosis (Psittacosis)