Product: Chlamydia trachomatis IgA ELISA
Chlamydia trachomatis IgA ELISA
Technology | ELISA |
Kit size | 96 Tests |
Sample material | Serum |
Sample preparation | 1:101 predilution |
Sample volume | 10 µl |
Standard range | Cut-Off |
Incubation | 60 min at 37°C, 30 & 15 min at RT |
Measuring system | TMB at 450 nm |
Sensitivity | >95 % |
Special remarks:
Chlamydiae are nonmotile, Gram negative and obligatory intracellular growing bacteria which form characteristic inclusions within the cytoplasm of parasitized cells. They are easily visible in the light microscope. Three different Chlamydia species pathogenic for humans are known: Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia psittaci, and one species only pathogenic for animals (C. pecorum). Chlamydia trachomatis is the most prevalent agent of sexually transmitted diseases worldwide (400-500 million cases) and the number of infections is constantly growing, during childbirth, causing conjunctivitis or pneumonia in newborns. Untreated cases of chlamydial infection can lead to chronic salpingitis, possibly resulting in ectopic pregnancy or infertility. In males, C. trachomatis is a major cause of non-gonococcal urethritis.
A severe problem in Chlamydia infections is the frequent asymptomatic insidious course which may result in the initiation of chronic diseases. In many instances primary infections are not recognized and only the sequelae caused by ascended, persisting agents are diagnosed.
Species | Mechanism of infection | Disease | Diagnostics |
C. trachomatis
|
Direct or sexual transmission: The primary site of infection usually is the mucous membrane of the eye or the urogenital tract |
Lymphogranuloma venereum (LGV) Trachoma Inclusion conjunctivitis of neonates and adults; Cervicitis, salpingitis, urethritis, epididymitis, proctitis and pneumonia of newborns |
Serology
PCR
Microscopy |
C. pneumoniae
|
Infiltration of the mucous membrane of the respiratory tract |
Respiratory diseases discussed: endocarditis, coronary heart diseases | |
C. psittaci
|
Inhalation of feces from infected birds; contact with infected avian viscera
|
Ornithosis (Psittacosis) |





