Novelty available: TNF-alpha ELISA CE-marked!
From now on Demeditec Diagnostics can supply a CE-marked TNF-alpha ELISA.
The Enzyme immunoassay for the quantitative determination of Tumor Necrosis Factor - α (TNF-α; Cat. #DE75111) in human serum, plasma and cell culture supernatants is available CE-marked from now on!
Click here to view the product site of the TNF-alpha ELISA!
Tumor necrosis factors (or the TNF-family) refer to a group of cytokines whose family can cause cell death (apoptosis). The first two members of the family to be identified were:
- Tumor necrosis factor (TNF), formerly known as TNF-α, is the best-known member of this class. TNF is a monocyte-derived cytotoxin that has been implicated in tumor regression, septic shock and cachexia. The protein is synthesized as a prohormone with an unusually long and atypical signal sequence, which is absent from the mature secreted cytokine. A short hydrophobic stretch of amino acids serves to anchor the prohormone in lipid bilayers. Both the mature protein and a partially processed form of the hormone can be secreted after cleavage of the propeptide.
- Lymphotoxin-alpha, formerly known as Tumor necrosis factor-beta (TNF-β), is a cytokine that is inhibited by interleukin 10.
If you need further information please contact us directly by sending an email to: info(at)demeditec.de.
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